fjgoodluck 发表于 2010-9-4 00:03

Window period

英语好的请翻译下!!

Window period
Antibody tests may give false negative (no antibodies were detected despite HIV being present) results during the window period, an interval of three weeks to six months between the time of HIV infection and the production of measurable antibodies to HIV seroconversion. Most people develop detectable antibodies approximately 30 days after infection, although some seroconvert later. The vast majority of people (97%) have detectable antibodies by three months after HIV infection; a six-month window is extremely rare with modern antibody testing. During the window period, an infected person can transmit HIV to others although their HIV infection may not be detectable with an antibody test. Antiretroviral therapy during the window period can delay the formation of antibodies and extend the window period beyond 12 months. This was not the case with patients that underwent treatment with post exposure prophylaxis (PEP). Those patients must take ELISA tests at various intervals after the usual 28 day course of treatment, sometimes extending outside of the conservative window period of 6 months. Antibody tests may also yield false negative results in patients with X-linked agammaglobulinemia; other diagnostic tests should be used in such patients.

Three instances of delayed HIV seroconversion occurring in health-care workers have been reported; in these instances, the health-care workers tested negative for HIV antibodies greater than 6 months postexposure but were seropositive within 12 months after the exposure. DNA sequencing confirmed the source of infection in one instance. Two of the delayed seroconversions were associated with simultaneous exposure to hepatitis C virus (HCV). In one case, co-infection was associated with a rapidly fatal HCV disease course; however, it is not known whether HCV directly influences the risk for or course of HIV infection or is a marker for other exposure-related factors.

http://en.wikipedia.org/wiki/HIV_test

shangguanxi 发表于 2010-9-4 00:28

在窗口期内抗体检测将会是错误的,窗口期是3周-6个月!大多数人的抗体可被发觉在30天后!但是一些人的血清转化会比较迟缓巨大的人群会出现抗体在3个月! 6个月是极其罕见的概率出现的!在窗口期一个人是可以感染给他人的!如果在窗口期内进行了 逆转录治疗 会延长窗口期到1年!...............
大概就是这些了!下面一段讲的差不多是HCV什么的
我有个疑问 我看中央电视台科教频道 的医生职业暴漏在服药1一个月后 也是检查了6周 然后上岗的!晕!

Mcnbasotl 发表于 2010-9-4 03:10

不会吧,疾控中心操作手册规定,暴露阻断后,要查到6个月的。
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