一篇非常牛的文章，与恐手指伤口的大家分享

我非常害怕2011

In fingering, only menstrual blood carries any significantly infectiousfluids. This is because the vaginal secretions found in the vaginalwalls and the opening of the vagina are relatively uninfectious. it isthe cervical fluids, deeper in the vaginal area, which pose a greaterinfectivity risk due to a higher concentration of active HIV.

NoteI use the term ACTIVE and not alive. technically, HIV is not alive. Itcannot reproduce on it's own. It requires a very specific type of whiteblood cell to infect with it's genetic material and essentially turninto an HIV producing factory. These receptive cells are commonly foundin the urethra, in the dendritic cells under an uncircumsized foreskin,in the anus, and in the vagina. To a far lessor degree, there are somein the tonsil area as well.

So we have established that even ifinfectious fluids got into a cut in your finger, they would have totravel through your bloodstream and encounter one of these receptivecells. Not as likely event, at all. To the point where forcing it tohappen in a lab using monkeys/primates and SHIV is largelyunsuccessful. In a petri dish? Perhaps. In a bipedal organism?Difficult, if not impossible to achieve.

Now, about thoseinfectious fluids. You realize that HIV mutates constantly, correct?Part of it's difficulty as regards a cure or vaccine is this constantmutation. Not the sort of mutation that makes a blood-borne pathogenairborne, but one which, in the long run, helps it to survive. HIVwears down an immune system by stimulating an immune response once thehost is infected. And the host then produces antibodies, which destroythe viral particles and infected cells that are recognized.

Atthis point in infection, almost all the HIV is purged temporarily fromthe blood. However, reservoirs in the brain, organs, and lymphaticsystem are still there, and they mutate just enough so that the bodymust re-recognize them and mount another immune defense. This goes onfor years and years in most cases, until the ability of the body tomount further defenses is compromised to the point where the immunesystem basically collapses. During this time, the host is left more andmore defenseless against common pathogens, until finally it succumbs,either to an external pathogen or an internal function that an intactimmune system would otherwise regulate.

Knowing this, andkeeping in mind that the virus constantly mutates, it is not aparticularly efficient virus. Most of the mutations are worthless,lacking one protein or another which makes it basically inactive,unviable. It is Darwinism at a miscroscopic scale, and greatly advanced.

See,the perfect HIV, the "goal," if you will, of HIV is to infect a hostand reproduce and spread without killing the host. Not due to anyaltruism on it's part, but a dead host can't infect others. This is whyoutbreaks of Ebola and Marberg viruses are almost always brief andcontained. it would take much engineering to reproduce a species-killerlike "The Stand." It would involve a virus behaving in a totallydifferent fashion than any other.

So the odds of an active,VIABLE viral particle finding it's way INTO your bloodstream, finding areceptive white blood cell (dendritic and T cells) and thensuccessfully injecting it with it's genetic material - through a cut inthe FINGER which almost instantly seals itself from external danger,and which bombards the area with elements specifically dsigned toprotect and heal the skin - is purely in the realm of the theoretical.Why is there so little research? because it can't be forced to happenwith any regularity in a lab, in a primate, in a monkey.

It hasnever been documented to happen. In the real world, the one we live in,it does not happen. It is hell on wheels to even make something likethat occur in a carefully monitored laboratory. Even a petri dish is nofriend to HIV.

Why do some doctors and scientists still caution?Because people mired in academia are rarely in touch with the actual,quantifiable world. The notion of "theoretical risk" and 'actual risk"are merged into a single hysterical message. There is a theoreticalrisk that a planet-destroying asteroid will smash the earth. There is atheoretical risk that our sun will explode. I think you get my intenthere.

Let me recap:

Vaginal secretions: extremelyunlikely to infect even if exposed to dendritic cells. Thus,cunnilingus is not considered a viable HIV risk.

Fingers: self sealing, and not containing receptive cells which HIV needs in order to infect.

That's not me talking, it's the science and the epidemiology talking.

Sources:

http://www.aegis.com/news/ads/1988/ad880100.html

http://www.aegis.com/aidsline/1990/may/m9050993.html

http://www.aegis.com/conferences/iac/2002/thpec7405.html

这是发在aidsmeds上的一篇长文，原文不翻译了，结论是：
阴道分泌物：及时接触到淋巴细胞（树突什么的，这里翻译成淋巴细胞）也不会感染。所以，舔阴不会有可能的风险。
手指：自愈（可能翻译成自封？），并且没有接受感染的细胞。