一段证明四代四周论的文字

我非常害怕2011

Thanks for the clarification.  I won't get into a debate with otheronline resources.  However, I will point out that the moderators ofMedHelp's international HIV forum agree that a negative combo (duo)test at 4 weeks is just as definitive as a 3 month antibodytest.  Significantly, those moderators are in the UK, where the combotest has been in use for a few years.

The manufacturers' formal advice (and their FDA-approvedinterpretation) for antibody-only testing is that it can take 3 monthsto convert to positive, and many American providers and experts tend tostick with that advice for medicolegal safety -- even though there aresolid data for 6-8 weeks.  No matter how strong new data may be, themanufacturer of a test may not legally claim a new standard until andunless they conduct their OWN research and submit the results to FDA --an expensive process, so it rarely happens.  (Same thing when drugs arefound to work for medical conditions or in doses which were notinitially approved by FDA.  Some of CDC's own recommendations for STDtreatment advise drug doses that are not approved by the FDA.)  As longas the manufacturer of a test or drug legally must stick with a certainstandard, you can understand why many doctors, health departments, CDC,and other advisors feel compelled to adhere to the same advice.

The combo HIV p24/antibody test has only recently been approved bythe FDA for use in the US and there is not yet much clinical experiencewith it.  My understanding is that the manufacturer has FDA approval toclaim 99% (maybe it's 99.9%, I'm not sure) reliability 4 weeks afterexposure, and I anticipate this interpretation will gradually diffuseto all US based providers and health departments.  But it may take awhile.

by H. Hunter  Handsfield, M.D., Sep 18, 2010 05:25PM                        

zl1981

    有谁能翻译下不

我非常害怕2011

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黑体字：

MedHelp的主持人认为四代酶联（检测抗原及抗体）在四周阴和三代（检测抗体）三个月阴是一样效果的。那些主持人是在已经使用四代酶联一些年的英国的。

本人的理解是制造商拥有FDA的证明，认为四代酶联在四周后检测有99%（或99.9%，没有很确定）的准确，预计这种说法将扩散到全美，虽然仍然需要一段时间。

zl1981

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   看来新观点的科技的推广，需要一段时间~

wopaqqq

其实你看论坛里的几率 5周就是99.9几了.为啥还有人测8周测3月呢?